Knighthood: Dr. Flox and Brutos 400% Alchemist Build Guide

To run the 400% Alchemist build in Knighthood, pair Dr. Flox and Brutos at level 70 with the Holy Gauntlet, stack enough Alchemist Hero Charms across your armor to reach a 400% modifier, and complete your Codex Library research for Golems and Goblins. This setup converts gauntlet punches and Brutos’s base power into immediate Rage meter refills, allowing Dr. Flox to repeatedly fire high-damage Rage powers against endgame waves.

Build Requirements

Both heroes share the Alchemist class, meaning every class-specific charm and research bonus applies to both heroes simultaneously.

Component	Target Spec	Primary Purpose
Dr. Flox	Level 70	Primary damage dealer via heavy Rage skill scaling
Brutos	Level 70	Generates Rage, applies Protect, and strips armor
Gauntlet	Holy Gauntlet	Accelerates Alchemist skill charge speed through punching
Armor Charms	400% Alchemist Power	Triangle slots dedicated to Alchemist hero power
Codex Library	Golem & Goblin trees	Increases damage output against Golem and Goblin enemy types

How the Holy Gauntlet Synergy Works

The Holy Gauntlet drives the speed of this composition. Its passive speed boosts charge Alchemist base powers significantly faster when you use punch attacks rather than standard weapon attacks.

Rapid Base Charge: Landing Holy Gauntlet punches quickly readies Brutos's base skill.
Rage Refill and Protection: Triggering Brutos's base power applies the Protect buff to your Knight and instantly fills a massive portion of your Rage gauge.
Flox Burst Execution: With the Rage meter filled, trigger Dr. Flox's Rage power immediately. Flox delivers heavy explosive damage scaled by the 400% Alchemist charm modifier.

Because Brutos reliably refills your Rage bar, you do not have to spend turns slowly accumulating Rage through conventional weapon strikes.

Charm Allocation and Library Bonuses

Reaching the 400% power threshold requires prioritizing gear pieces that feature triangle Hero Charm slots.

Charm Stacking: Slot high-tier Alchemist Hero Power charms across your armor until your total modifier reaches 400%. Splitting slots into defensive runes or other hero archetypes reduces Flox's ability to eliminate high-tier targets in single rotations.
Library Research: Maximize the research nodes for Golems and Goblins in the Codex Library. High-level encounters frequently feature frontline Golem tanks and disruptive Goblin packs. Library nodes provide targeted percentage modifiers that scale on top of your 400% charm baseline, preventing Flox’s explosive burst from stalling against armored targets.

Turn-by-Turn Combat Rotation

To maintain continuous ability uptime, follow this action sequence:

Charge Base Powers: Open the encounter with Holy Gauntlet punches against frontline targets to fill your hero meters.
Deploy Brutos First: Activate Brutos's base power as soon as it is available. This secures your Protect buff and fills your Rage meter.
Fire Dr. Flox’s Rage Power: Target the densest cluster of enemies or priority targets with Flox's Rage ability.
Cycle Punches: Spend your remaining action points on Holy Gauntlet punches to begin charging Brutos's base ability for the next turn.

Repeat this loop each round. Always trigger Brutos's base skill before using Flox's Rage ability so you never waste Rage meter generation or drop the Protect barrier.