Omniheroes Season 18 Rune Priority and Upgrade Guide

In Omniheroes Season 18, invest your rune resources first into Swiftness sets for action initiators and Striker sets for primary damage carries. Because enhancement stones and refinement materials are scarce, fully gearing your main damage dealer and primary turn-order controller yields significantly better results than distributing partial upgrades across an entire roster.

In the early game, complete two-piece or four-piece set bonuses regardless of sub-stats. As you progress into competitive player-versus-player (PvP) and late-game PvE towers, shift your investment toward hunting specific sub-stats, focusing on Speed and Attack percentage.

Season 18 Rune Priority Tier List

Offensive Runes for Damage Carries

Offensive runes determine how quickly your lineup eliminates enemy threats before opposing crowd control activates.

• Striker Sets: Equip a four-piece Striker set on multi-target burst heroes to maximize early-round offensive tempo through direct Attack scaling, Critical Rate, and Critical Damage multipliers.
• Hybrid Penetration Sets: If a carry already gains substantial Critical Rate from synergy passives, equip a two-piece Striker set paired with a two-piece Penetration set. This combination outperforms pure Attack sets against high-defense frontline tanks in high-level PvE and PvP brackets.

Sub-Stat Targets for Carries

When evaluating offensive runes, prioritize sub-stats in this order:

1. Attack % (ATK%): The foundational stat scaling skill damage and damage-over-time effects.
2. Critical Rate (Crit%): Aim for a baseline of 60% to 75% after accounting for active team buffs.
3. Critical Damage (Crit DMG): The most effective scaling multiplier once your Critical Rate meets the target threshold.
4. Armor/Damage Penetration: Essential against high-defense teams that blunt standard Attack scaling.

Defensive and Utility Runes for Frontline Stability

Frontline units require targeted survivability stats to endure opening bursts and allow your backline carries to cycle through their skills.

• Bastion and Guardian Sets: Equip these sets on frontline tanks to mitigate early burst damage. Prioritize Damage Reduction %, Health % (HP%), and Dodge over flat defense, as flat defensive stats scale poorly in high-difficulty content.
• Sanctuary Sets: Equip Sanctuary runes on sustained healers and heroes whose abilities scale with maximum health. This amplifies total HP pools and increases incoming healing received.

Speed Tuning and Turn Order

Speed determines which team acts first to apply debuffs, strip enemy shields, or inflict crowd control.

Equip your highest-speed Swiftness pieces on support initiators rather than your primary damage dealer. For an effective combat sequence:

1. Debuffer or Buffer (Fastest): Must move first to strip defensive shields or apply damage amplification to the enemy team.
2. Main Damage Carry (Second): Must act immediately after the debuffer to strike targets while defense shred is active. Attacking before your debuffer wastes substantial burst potential.

Rune Upgrading and Refinement Rules

To avoid resource bottlenecks, follow strict stopping points when upgrading and rerolling rune stats.

Upgrade Milestones

• Incremental Testing: Upgrade promising runes to +3 or +6 first.
• Stopping Point: If a piece with base Speed or Attack % repeatedly upgrades into flat HP or flat defense, stop leveling it. Reserve that piece as enhancement material for higher-potential gear.

Refinement and Stat Locking

• Rarity Restriction: Save refinement stones exclusively for red-grade and top-tier legendary runes belonging to high-priority sets (Swiftness or Striker).
• Locking Strategy: Only lock Speed or top percentage attributes during refinement. The currency cost to lock multiple lines increases sharply with each locked slot.
• Lineup Progression: Fully optimize two complete sets for your primary lineup before spending resources on backup sets for secondary teams.