Saints Row: The Third - The Trouble With Clones DLC Strategy Guide

To complete The Trouble With Clones DLC in Saints Row: The Third, upgrade your weapon damage before starting, rely on explosive loadouts, and shoot aggressively for headshots. Mutated clones feature high health pools and rapid movement, making target prioritization, high-ground control, and strategic ally usage essential to survival.

Loadout Preparation and Target Prioritization

Mutated clones possess significantly more health and mobility than standard Syndicate enemies. Body shots yield poor stopping power against aggressive melee clones, making headshots mandatory for fast clears.

Before initiating DLC missions, visit a weapon store to purchase damage upgrades for your core gear.

• Shotgun: Essential for close-range crowd control when melee clones swarm your position.
• RPG and Grenade Launcher: Use these to instantly break dense groups in corridors or tight laboratory rooms.
• Sustained Fire Secondary: Carry an automatic secondary weapon to pick off surviving enemies without getting caught in slow explosive reload animations.
• Ammunition Management: Scavenge weapons dropped by defeated clone waves to maintain heavy ordnance ammo during long firefights.

Positioning, Cover, and Team Tactics

The multi-tiered laboratory levels in this DLC require careful movement and positional control to avoid getting overwhelmed.

1. Gain Vertical Advantage: Move quickly to elevated platforms or staircases. Controlling the high ground opens clean lines of sight for headshots while forcing melee clones into long, exposed approaches.
2. Funnel Enemies into Choke Points: Avoid standing in open spaces where rapidly closing clones can flank you. Retreat behind doorway chokepoints and utilize hard cover like pillars or vending machines during reload cycles.
3. Clear Side Rooms: When advancing toward primary objective markers, defeat minor enemies in adjacent rooms to secure your rear line before starting timed or escort tasks.
4. Use Allies as Distractions: Allow friendly Saints NPCs to enter rooms first. While clone AI focuses on your companions, single out high-damage threats.
5. Delay Risky Revives: If a companion goes down during a heavy wave, clear the immediate area or secure the objective before attempting a revive to avoid taking lethal damage.